{"id":2477,"date":"2025-08-21T17:53:06","date_gmt":"2025-08-21T08:53:06","guid":{"rendered":"https:\/\/mediwhale.stage.studio-jt.co.kr\/kr\/?post_type=publication&#038;p=2477"},"modified":"2025-08-21T17:53:06","modified_gmt":"2025-08-21T08:53:06","slug":"quantifying-the-repeatability-and-reproducibility-of-dr-noon-cvd-an-artificial-intelligence-software-as-medical-device-for-cardiovascular-risk-assessment-via-retinal-imaging","status":"publish","type":"publication","link":"https:\/\/mediwhale.stage.studio-jt.co.kr\/ko\/publication\/quantifying-the-repeatability-and-reproducibility-of-dr-noon-cvd-an-artificial-intelligence-software-as-medical-device-for-cardiovascular-risk-assessment-via-retinal-imaging\/","title":{"rendered":"Quantifying the repeatability and reproducibility of Dr.Noon CVD, an artificial intelligence software as medical device for cardiovascular risk assessment via retinal imaging"},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">Abstract<\/h4>\n\n\n\n<h4 class=\"wp-block-heading\">Purpose<\/h4>\n\n\n\n<p>To evaluate the repeatability and reproducibility of the Dr.Noon CVD, an artificial intelligence software as a medical device that assesses cardiovascular risk from retinal photographs by providing risk scores and classifying patients into three categories: category 0 (low risk), category 1 (intermediate risk), and category 2 (high risk).<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Methods<\/h4>\n\n\n\n<p>In this prospective, single-center study, participants underwent nonmydriatic fundus photography. For repeatability assessment, one examiner captured 3 consecutive images per eye. For reproducibility, a second examiner independently acquired 1 image per eye. Intraclass correlation coefficients (ICCs), within-subject standard deviations, and coefficients of variation were calculated. Differences by risk category and lens status were assessed using ANOVA and independent&nbsp;<em>t<\/em>&nbsp;tests.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Results<\/h4>\n\n\n\n<p>Overall, Dr.Noon CVD demonstrated excellent reliability, with a repeatability ICC of 0.997 (95% confidence interval [CI]: 0.996\u20130.998) and a reproducibility ICC of 0.999 (95% CI: 0.998\u20130.999). When analyzed by risk categories, repeatability, and reproducibility ICCs were 0.985 (95% CI: 0.974\u20130.997) and 0.995 (95% CI: 0.990\u20130.997) for category 0, 0.960 (95% CI: 0.918\u20130.983) and 0.969 (95% CI: 0.921\u20130.988) for category 1, and 0.965 (95% CI: 0.943\u20130.980) and 0.984 (95% CI: 0.971\u20130.992) for category 2. In terms of lens status, phakic eyes showed repeatability and reproducibility ICCs of 0.998 (95% CI: 0.996\u20130.998) and 0.999 (95% CI: 0.998\u20130.999), respectively, while pseudophakic eyes showed slightly lower but still excellent values of 0.989 (95% CI: 0.980\u20130.995) and 0.994 (95% CI: 0.988\u20130.997).<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Conclusions<\/h4>\n\n\n\n<p>Dr.Noon CVD demonstrated high precision with excellent repeatability and reproducibility across all risk levels and lens statuses, supporting its reliability for cardiovascular risk screening using retinal images.<\/p>\n","protected":false},"template":"","publication_type_categories":[11],"publication_categories":[16],"class_list":["post-2477","publication","type-publication","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/mediwhale.stage.studio-jt.co.kr\/ko\/wp-json\/wp\/v2\/publication\/2477","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mediwhale.stage.studio-jt.co.kr\/ko\/wp-json\/wp\/v2\/publication"}],"about":[{"href":"https:\/\/mediwhale.stage.studio-jt.co.kr\/ko\/wp-json\/wp\/v2\/types\/publication"}],"version-history":[{"count":1,"href":"https:\/\/mediwhale.stage.studio-jt.co.kr\/ko\/wp-json\/wp\/v2\/publication\/2477\/revisions"}],"predecessor-version":[{"id":2478,"href":"https:\/\/mediwhale.stage.studio-jt.co.kr\/ko\/wp-json\/wp\/v2\/publication\/2477\/revisions\/2478"}],"wp:attachment":[{"href":"https:\/\/mediwhale.stage.studio-jt.co.kr\/ko\/wp-json\/wp\/v2\/media?parent=2477"}],"wp:term":[{"taxonomy":"publication_type_categories","embeddable":true,"href":"https:\/\/mediwhale.stage.studio-jt.co.kr\/ko\/wp-json\/wp\/v2\/publication_type_categories?post=2477"},{"taxonomy":"publication_categories","embeddable":true,"href":"https:\/\/mediwhale.stage.studio-jt.co.kr\/ko\/wp-json\/wp\/v2\/publication_categories?post=2477"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}